Posters Abstracts > North American Strong State Chemistry Conference 2021 > Usc Dana And David Dornsife College Of Letters, Arts And Sciences
Sequencing the Ugi-type MCRs with an intramolecular olefin formation through Staudinger/aza-Wittig39 or Wittig reaction40 was shown to be a well-known synthetic tool. Two selected applications for the preparation of libraries of biologically relevant heterocycles are shown in reactions B and C in Figure five. Which, instead of the standard acyl-transfer step terminating the Ugi reaction, underwent an intramolecular aza-Wittig occasion yielding the substituted 1,3,four-oxadiazoles (reaction A...